Morphology and immunophenotype in the LPHD cases with entirely diffuse growth pattern.

(A) By conventional histology, no evidence of nodularity was visible (H&E-stained; the neoplastic cells are highlighted with arrows). (B) Immunostains for CD20 showed that the positive neoplastic cells were arranged in a vaguely nodular pattern without evidence of admixed small B cells. (C) In several cases, the neoplastic cells showed an additional expression of J-chain.