Fig. 10.
IL-9 induces the proliferation of BMMCs through γc- and Jak3-dependent signaling.
BMMCs from WT, γc−, and Jak3−mice were cultured in the presence of IL-3 for 36 hours, with [3H] thymidine added for the final 12 hours. Where indicated, recombinant human IL-2, recombinant murine IL-7, recombinant murine IL-9, or recombinant human IL-15 was added at 20 ng/mL. Data are means ± SD for 5 mice in each group. *P < .005.