Fig. 2.
The structure of the
API2 gene and the adjacent API1gene on chromosome 11q22. The figure illustrates modifications from Young et al.13 PAC 166G16 spans both genes and is split by the translocation (Figure 3B). In the case of a deletion of chromosome 11 sequences distal to the breakpoint, the third hybridization signal on the derivative chromosome 18 may not be visible (Figure 3C).