Fig. 8.
Structures of the mutants of hMgcRacGAP.
Structures of the wild-type MgcRacGAP, R385A*MgcRacGAP (R385A*), and 2 deletion mutants lacking the myosin-like domain (ΔMyo) and the cysteine-rich domain (ΔCys) are shown together with the ability to induce growth suppression and differentiation of HL-60 cells.