Effects of IFN-α on AChE activity in cultures of CD41⁺/Lin⁻ marrow cells.

Purified MK progenitor cells were obtained as described in “Materials and methods,” and 1 to 1.5 × 10⁴/mL was placed in suspension culture with the indicated concentrations of mTPO and IFN-α. Results represent the mean AChE values of triplicate cultures of 4 independent experiments, except for the 1000 pg/mL mTPO data, for which only a single experiment was performed (hence, the absence of statistical significance). *P < .05 in comparison with cultures devoid of IFN-α.