Fig. 5.
Effect of blocking antibodies after 24 hours of TNF-α stimulation.
HDMECs were stimulated by TNF-α at 5 ng/mL for 24 hours. Experimental details are as for Figure 4 with the additional use of an anti–VCAM-1 MoAb (4B9). Results are mean ± SEM of 5 parasite isolates studied. (A) Effect of blocking antibodies on the rolling of IRBCs on stimulated HDMECs. (B) Effect of blocking antibodies on the adhesion of IRBCs on stimulated HDMECs.
