Fig. 1.
Clinical Trial Service Unit hazard score graph used to identify high-risk patients.
This graph was devised with MRC trial data from 1980 to 1990 using the prognostic variables of diagnosis, WBC count, sex, and age in an analysis of DFS. A boundary value that identified a subgroup of patients with a 5-year DFS of less than 40% was determined. In the graph, if the plot using a patient's age and diagnosis WBC count falls to the left of the appropriate sex line, the patient is at standard risk; if the plot falls to the right of the appropriate sex line, the patient's risk is high.6