Fig. 4.
sIgD− memory but not sIgDhigh naive B cells respond rapidly to MIP-3α/CCL20 by actin cytoskeleton reorganization.
The ability of CCR6 to signal in unstimulated tonsillar B cells stained with anti-IgD-PE MoAb was assessed by quantifying changes in intracellular F-actin after MIP-3α/ CCL20 stimulation (500 ng/mL). sIgD− (R3) responding and sIgDhigh (R2) nonresponding populations are shown. Data from one representative experiment of 3 are shown.