Fig. 1.
Each graph shows the comparison of AML samples versus ALL samples for 2 particular drugs.
The median LC50 value (dot) and the 25th and 75th percentile (triangles) are shown for each drug. The number of patients (n) for each group is shown at the bottom of the graph. P values, determined by the Mann-Whitney U test, are shown for statistically significant differences between AML and ALL. LC50 values are given as μg/mL, and values for l-asparaginase are given as IU/mL. In the prednisolone graph for AML, the 25th percentile is depicted as 250 μg/mL for practical reasons, but in reality it is greater than 250 μg/mL, which is above the highest concentration used in our assay. The median and P75 are not depicted for the same reason.