Comparison of the 3 AML FAB-type subgroups (FAB M1/M2, FAB M4, and FAB M5) as well as the total group of AML (including the other FAB types) as a reference group.

The data for ALL are depicted in the graph for both vincristine and l-asparaginase. The median LC50 value (dot) and the 25th and 75th percentiles (triangles) are shown for each drug. The number of patients (n) for each group is shown at the bottom of the graph. P values, as determined by the Mann-WhitneyU test, are shown only for statistically significant differences between the FAB-type subgroups (Table 4). LC50 values are given as μg/mL, and l-asparaginase values are given as IU/mL.