Fig. 7.
Example of an online measurement of O2− release in PMNs primed with TNF-α, as compared with unstimulated PMNs preincubated with supernatant from autologous degranulated PMNs.
Release of O2− radicals over 90 minutes is faster and greater in primed PMNs incubated with MPO-ANCA than in preincubated unstimulated PMNs exposed to MPO-ANCA. Similar results were obtained for 4 individual experiments.
