Infectivity of CD4⁺-enriched PBMCs with an M-tropic (SF162, left panels) and a T-tropic (LAI, right panels) virus.

PBMCs were treated for 8 hours without LPS (black bars) or with 100 ng/mL LPS (shaded bars) before being infected for 2 hours with 4-fold limiting dilutions of virus. After infection the cells were washed and cultured for an additional 10 days and viral infection was monitored by p24 production. Results of experiments with cells from 3 different donors are shown.