Fig. 7.
Chemotactic migration of PMN toward NAP-2 in the presence of PBP or CTAP-III.
NAP-2 precursors were mixed with NAP-2 at the concentrations indicated and were added to the lower compartment of the chemotaxis chamber. Subsequently, PMN (2 × 105/mL) was added to the upper chamber, incubated for 1 hour at 37°C, and numbers of migrated cells were determined. (A) Impact of increasing concentrations of PBP (▴) or CTAP-III (●) on PMN chemotaxis induced by 5 nmol/L NAP-2. Results are expressed as a percentage of the number of cells that migrated to 5 nmol/L NAP-2 alone. (B) Impact of 1 μmol/L PBP (▴) on the characteristic chemotactic response of PMN toward NAP-2. ▪, buffer. (A, B) Means ± SD of data obtained in 3 independent experiments are shown.
