Fig. 4.
Exogenous IL-6 abrogates 1α,25 dihydroxyvitamin D3-mediated growth inhibition of KS cells.
Inhibition of growth of KS Y-1 cells was determined by treatment of the cells with the indicated concentrations of 1α,25 dihydroxyvitamin D3 for 72 hours in the presence (■) or absence (▪) of rhIL-6 (10 ng/mL). Cell counts were determined with a Coulter Counter. The right-hand side of the graph (▧) shows the effect of rhL-6 alone on cell proliferation. Each value is the mean ± SEM of the assays performed in triplicate.
