Effect of calcipotriene on a KS lesion of an HIV-negative patient.

Calcipotriene ointment (0.005%) was applied twice daily to the lesion. (A) The tumor before initiation of treatment. (B) After 2 months. (C) After 18 months. (D) After 39 months. Tumor response is apparent at 2 months, with marked reduction after 18 months and complete resolution by 39 months.