Fig. 1. Antibacterial components in T... | American Society of Hematology

Fig. 1.

$Fig. 1. Antibacterial components in T cells and natural killer (NK) cells. / (A) Results of reversed-phase chromatography with the supernatant from T cells and NK cells stimulated with interleukin (IL)–2. The distribution of the antibacterial activity is indicated in the chromatographic profile by double-headed arrows. The characterized antibacterial components were α-defensins (HNP 1-3), lysozyme, a fragment of histone H2B, and LL-37. (B) Western blot analysis for the presence of LL-37 in chromatographic fractions. The chromatographic fractions 36 to 40, which were positive for LL-37 in dot-blot analysis, were further characterized by Western blotting. The lower band in fraction 36 to 38 corresponds to the mature LL-37, whereas the higher bands probably correspond to oligomeric forms.$

Antibacterial components in T cells and natural killer (NK) cells.

(A) Results of reversed-phase chromatography with the supernatant from T cells and NK cells stimulated with interleukin (IL)–2. The distribution of the antibacterial activity is indicated in the chromatographic profile by double-headed arrows. The characterized antibacterial components were α-defensins (HNP 1-3), lysozyme, a fragment of histone H2B, and LL-37. (B) Western blot analysis for the presence of LL-37 in chromatographic fractions. The chromatographic fractions 36 to 40, which were positive for LL-37 in dot-blot analysis, were further characterized by Western blotting. The lower band in fraction 36 to 38 corresponds to the mature LL-37, whereas the higher bands probably correspond to oligomeric forms.

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