Fig. 2.
Structure of cdb3 dimer.
(A) Ribbon diagram of cdb3 dimer showing interactions between interlocking dimerization arms. The positions of the 2 cysteines (Cys 201A and Cys 317B) that form an inter-subunit disulfide bond upon treatment with the oxidizing agent, o-phenanthroline/CuSO4(pH at least 7.5), are also shown. Because these cysteines cannot form a disulfide in the low pH conformation of cdb3, they are not expected to reside near each other in the low pH structure shown here. (B) Space filling model of cdb3 dimer. (C) Cluster of 9 leucine residues (extending from β11 and α10 of each subunit) that stabilize the dimerization domain.
