Fig. 6.
![Fig. 6. Differential recruitment of the coactivator ACTR by wild-type and mutant PML/RARα fusion proteins on a DR5 RARE in gel mobility shift assay. / Interaction of ACTR with wild-type and mutant PML/RARα S-form (A) and L-form (B). In vitro translated PML/RARα fusion proteins were coincubated with the [32P]-labeled DR5 RARE, along with bacterially expressed GST-ACTR-RID in the presence of increasing concentrations of RA. The position of the complex shifted by ACTR indicated.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/9/10.1182_blood.v96.9.3200/5/h82100300006.jpeg?Expires=1735839562&Signature=bhJaeN3oD0vSFFNXFsu~3731-FOVQxnxKVvbTK4S-lFEXjH8Q2coX819yKzYr7nQv6P7~SgPwhZ1tZZ1YBz~gV1aKsZTVH3Z~8yoJI2rmGYG22Wjks8epP6B0t4ipOyxMDsntmiuR1DINpzSPWKWzjHCxLNoEpUoPEs0fxhXOdbH1K1htf9MeAHcMgEIQLgW0QK4gi2P~NbVlTU52PBTWCQtPpG-N~a0~c6dpLZ0KCOwTqzzSSppql9jjya6LBbr7TBGyuqlJlFP0SYVX-Wu6BVqKqyXE8TOg0lyQwQALkFFzNh7XOaLTqwHEBJQOkxs0Ud4eaO47~tyM6nzYfiVlA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Differential recruitment of the coactivator ACTR by wild-type and mutant PML/RARα fusion proteins on a DR5 RARE in gel mobility shift assay.
Interaction of ACTR with wild-type and mutant PML/RARα S-form (A) and L-form (B). In vitro translated PML/RARα fusion proteins were coincubated with the [32P]-labeled DR5 RARE, along with bacterially expressed GST-ACTR-RID in the presence of increasing concentrations of RA. The position of the complex shifted by ACTR indicated.
