Fig. 6.
![Fig. 6. Constitutive expression of dominant negative Stat1HAY701F inhibits ATRA-induced differentiation into a morphologically mature monocytic phenotype. / (A, B) pCIneo, (C, D) Stat1(HA).7, and (E, F) Y701F.8 cells were grown with (B, D, F) or without (A, C, E) ATRA for 5 days and cytospin preparations were examined by May-Grünwald-Giemsa staining. (i, ii, iii) Enlargements of cells indicated by arrows in panels B, D, and F. (Magnification [A-E] 1:400; [i, ii, iii] 1:1200).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/8/10.1182_blood.v96.8.2870/5/h82000240006.jpeg?Expires=1736055657&Signature=Up~Xa7kqMaMiG2uP3qCvQzJi3lZhhQY3lP-nLIGa6vClETlzCiC2phsWRfvOgdCjxsJwh5v1hj8dxHlemp~UfMNR-JCCiq-9vLlCFtiUpIvo4fqXeIvzY-UhQ0O8YbDmVaABxweABzGhESEJ3FO03asCjPpATWdRsZ3N~zhYvMF-IsBQ-dsYGiOe1OccT-59jUr3pMmRGGbFAF9yayZloRrIxudxe-v3MhWeS3p3TRRvTULcIgYx-eIc8rf6dTdqs0I3WH8VRpNwAtCMDEK56~EDbpg82urUolRvXivZh1kYsA51LRhFdUqjoZ3-t7i-W6bordCRfnMifAGo6vihwg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Constitutive expression of dominant negative Stat1HAY701F inhibits ATRA-induced differentiation into a morphologically mature monocytic phenotype.
(A, B) pCIneo, (C, D) Stat1(HA).7, and (E, F) Y701F.8 cells were grown with (B, D, F) or without (A, C, E) ATRA for 5 days and cytospin preparations were examined by May-Grünwald-Giemsa staining. (i, ii, iii) Enlargements of cells indicated by arrows in panels B, D, and F. (Magnification [A-E] 1:400; [i, ii, iii] 1:1200).
