Distribution of HA in HCL tissues.

Tissue sections were stained with HRP-conjugated HA binding protein (see “Materials and methods”). In bone marrow, a reticular network of HA is clearly seen. In portal tracts, the HA is associated with the dense matrix. Splenic red pulp lacks HA, whereas the residual white pulp is positive. In the hepatic sinuses, only the macrophages are stained.