Fig. 5.
Distributions of simulated data using the best parameter values.
The results derive from 150 data sets of 44 mice given transplants (6600 simulated murine transplantations). The distribution of the percentage of donor granulocytes at 6, 15, and 30 weeks after these simulated transplantations is shown. In (A), parameter values are 1 per 2.5 weeks for λ, 1 per 3.4 weeks for ν, 1 per 20 weeks for α, 1 per 6.9 weeks for μ, 35 HSCs for R0, and 50 clones for C0. For the simulations of (B), R0:C0 was arbitrarily set equal to 1:4. To achieve these results,R0 was 18 HSCs and thus HSC frequency was 4 per 105 nucleated marrow cells.
