Fig. 3.
Effects of HIV-protease inhibitors on CD11b expression of HL-60 cells and CD66b expression on NB4 cells.
(A) HL-60 cells were cultured for 5 days with either ATRA (10−11-10−9 mol/L) alone or in combination with either indinavir (2 × 10−5 mol/L), ritonavir (1 × 10−5 mol/L), or saquinavir (1 × 10−5 mol/L), and then analyzed by FACscan for expression of CD11b. (B) NB4 cells were cultured for 5 days with either ATRA (10−10-10−9 mol/L) alone or in combination with indinavir (2 × 10−5 mol/L), ritonavir (0.5 × 10−5 mol/L), or saquinavir (0.5 × 10−5 mol/L), and then analyzed by FACscan for expression of CD66b. These results represent 3 independent experiments.