Fig. 4.
NBT reduction.
The effects of HIV-1 protease inhibitors on NBT reduction of HL-60 (A) and NB4 (B) are shown. Cells were cultured for 5 days with various concentrations of ATRA (10−8-10−7 mol/L for HL-60; 10−10-10−9 mol/L for NB4) either alone or in combination with either indinavir (2 × 10−5mol/L), ritonavir (1 × 10−5 mol/L), or saquinavir (1 × 10−5 mol/L), and differentiation was determined by NBT reduction. Figure shows results of 3 independent experiments.