Fig. 2.
![Fig. 2. The inhibitory effects of ADP scavengers on serotonine secretion evoked by FcγRIIA is reversed by epinephrine. / Platelets were previously loaded with 5-hydroxy[14C]tryptamine, and secretion was determined as described in “Materials and methods.” A3P5PS, CP-CPK, and CP-CPK and 1-μmol/L epinephrine were added 1 minute before stimulation by FcγRIIA cross-linking. The effect of 1-μmol/L epinephrine alone was also assessed. Data are the mean of 2 independent experiments. (A) Stimulation by FcγRIIA cross-linking; (B) stimulation by HIT sera.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/10/10.1182_blood.v96.10.3439/5/h82200374002.jpeg?Expires=1735515308&Signature=MCN3ULY6gtgdkSsAIZn0kk12A8XKmtyAdcCyNs3K5wVp2qZc7V0b6S-oWKq4kz0pD-lY5IaWgovly6EtBZXePnUg23nL06wa9zfXcKrrmrwJdpeCouh5PNjLIxgkAatrbK2klc6edcglJN2aGK8XNF5I08kxBJ3c1jVJFi7M0nAYG3mJCN-zl-x2CpvBbr0tWDIUzDIdhluKv9VcxLxum34OiHRo~QX1AF8t~L-yfZm1hZbJeCdqnaxbNGv~YfHnDI81b7AZzFv~m1ck88zr63bO1Nhvm83kzL~dTIoQviBHth~~OQ4bsjLqR7Zz9HSeoJGb4Chf3rbOVDVpHfF79A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The inhibitory effects of ADP scavengers on serotonine secretion evoked by FcγRIIA is reversed by epinephrine.
Platelets were previously loaded with 5-hydroxy[14C]tryptamine, and secretion was determined as described in “Materials and methods.” A3P5PS, CP-CPK, and CP-CPK and 1-μmol/L epinephrine were added 1 minute before stimulation by FcγRIIA cross-linking. The effect of 1-μmol/L epinephrine alone was also assessed. Data are the mean of 2 independent experiments. (A) Stimulation by FcγRIIA cross-linking; (B) stimulation by HIT sera.
