Expression of MT1-MMP on platelet membranes.

(A) Human mesangial cell membranes (HMCs, lane 1), HMC membranes treated by urokinase (100 nmol/L for 24 hours) (lane 2), human resting platelet membranes (lane 3), and aggregated platelet membranes (lane 4) were analyzed by immunoblotting using an antihuman MT1-MMP monoclonal antibody. (B) Human platelet membranes were analyzed by immunoblot in nonreduced and reduced conditions.