Fig. 1.
Fibrin(ogen) deficiency does not reduce the growth rate of subcutaneously transplanted LLC.
A single cell suspension of 5 × 105 LLC cells was injected subcutaneously into the dorsal, midscapular skin of Fib− (n = 16) and control (n = 19) mice. The individual tumor volumes were measured daily by calipation. The data presented are mean values and SDs for each time point. No significant difference was noted in tumor growth between Fib− and control mice (P > .6, random coefficient mixed model).
