American Society of Hematology

Fig. 2.

$Fig. 2. Expression of p53 protects U266 cells from Dox- and Mel-induced apoptosis. / Cells were incubated in the absence of IL-6 for 3 days before each treatment. Cells were treated with IL-6, Dox, or Mel as indicated and were harvested on days 2 and 4 for cell cycle and apoptosis analyses. Percentages of cells in each stage of the cell cycle were determined by PI staining of nuclei and then by flow cytometry analysis. The number in the left corner represents the apoptotic fraction, and the number in the right corner represents the combined S and G2/M stages of the cell cycle. Data shown are representative of at least 3 independent experiments.$

Expression of p53 protects U266 cells from Dox- and Mel-induced apoptosis.

Cells were incubated in the absence of IL-6 for 3 days before each treatment. Cells were treated with IL-6, Dox, or Mel as indicated and were harvested on days 2 and 4 for cell cycle and apoptosis analyses. Percentages of cells in each stage of the cell cycle were determined by PI staining of nuclei and then by flow cytometry analysis. The number in the left corner represents the apoptotic fraction, and the number in the right corner represents the combined S and G2/M stages of the cell cycle. Data shown are representative of at least 3 independent experiments.

This Feature Is Available To Subscribers Only