Fig. 6.
Release of IP3 from fibroblasts stimulated with FVIIa, FFR-FVIIa alone, or FFR-FVIIa in combination with PDGF-BB.
Cells were labeled overnight withmyo-[3H]-inositol, incubated with or without 100 nmol/L FVIIa or FFR-FVIIa in the absence or presence of 10 ng/mL or 100 ng/mL PDGF-BB. Cells were then analyzed for release of IP3. Open bars show cells without FVIIa or FFR-FVIIa (control), hatched bars show cells with FFR-FVIIa, and filled bars show cells incubated with FVIIa.