Fig. 5.
Reduction of cyclin A1 protein levels by ATRA in NB4 cells but not in ATRA-resistant NB4-R2 cells.
Immunoblot analysis showing cyclin A1 protein levels in NB4 cells at 0, 24, and 72 hours of exposure to ATRA (10−6 mol/L). On each lane, 20 μg total protein was loaded. An anti-actin antibody was used to demonstrate equal loading.