IL-1β inhibits IL-6-mediated γ fibrinogen gene expression.

(A) Total RNA was prepared from rat primary hepatocytes following treatment with IL-1β and IL-6 as indicated. The arrows on the right side indicate the migration positions of rat γ fibrinogen mRNA and cyclophilin mRNA, respectively. (B) Total RNA was prepared from human hepatoma HepG2 cells following treatment with IL-1β and IL-6. The arrows on the right side indicate the migration positions of human γ fibrinogen mRNA and GAPDH mRNA, respectively. The graphic represents the quantification results from one experiment of 2 independent studies.