Fig. 8.
Effects of Sph-1-P or LPA on HUVEC [Ca++]i.
(A) Fura2-loaded HUVECs were challenged with 1 μmol/L Sph-1-P or LPA. Changes in [Ca++]i were monitored by the ratio of fura2 fluorescence. Arrows indicate the addition of Sph-1-P and LPA. (B) Fura2-loaded HUVECs were stimulated with various concentrations of Sph-1-P (○) or LPA (●), and the increases in [Ca++]i (the ratio of fura2 fluorescence) were measured.