Fig. 5.
Survival of SCID mice injected with 32Dc13 cells expressing BCR/ABL, Bcl-2, p185ΔBCR/Bcl-2, p185ΔBCR/M-Raf-1, or p185ΔBCR/Bcl-2/M-Raf-1.
Mice were injected intravenously with 5 × 106 cells from parental or transfected 32Dc13 cells. Nine mice were included in the wild-type BCR/ABL group; 5 mice, the Bcl-2 group; 10 mice, the p185ΔBCR group; 24 mice, the p185ΔBCR/Bcl-2 group (8 mice for each of 3 clones); 14 mice, the p185ΔBCR/M-Raf group (7 mice for each of 2 clones); and 8 mice, the p185ΔBCR/Bcl-2/M-Raf-1 group.
