Fig. 7.
Fig. 7. Southern blot analysis of the Bcl-2 locus in p185ΔBCR/Bcl-2 clones before injection in SCID mice and in leukemic cells recovered from the spleen. / Southern blot of genomic DNA from p185ΔBCR 32Dc13 clones (left panel), p185ΔBCR/Bcl-2 clones (middle panel), and p185ΔBCR/Bcl-2 clones recovered from the spleen of leukemic mice (right panel). Genomic DNA was digested with HindIII, BamHI, orXbaI (from left to right), electrophoresed on a 0.8% agarose gel, transferred to nylon membranes, and hybridized to a32P-labeled Bcl-2 fragment.

Southern blot analysis of the Bcl-2 locus in p185ΔBCR/Bcl-2 clones before injection in SCID mice and in leukemic cells recovered from the spleen.

Southern blot of genomic DNA from p185ΔBCR 32Dc13 clones (left panel), p185ΔBCR/Bcl-2 clones (middle panel), and p185ΔBCR/Bcl-2 clones recovered from the spleen of leukemic mice (right panel). Genomic DNA was digested with HindIII, BamHI, orXbaI (from left to right), electrophoresed on a 0.8% agarose gel, transferred to nylon membranes, and hybridized to a32P-labeled Bcl-2 fragment.

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