Neoplastic plasma cells express significantly higher levels of CD126 and CD130 than normal plasma cells.

Box and whisker plots showing the minimum; 25th, 50th, 75th percentiles; and maximum expression of (A) CD126 (IL-6 receptor alpha-chain) and (B) CD130 (IL-6 receptor beta-chain) by normal and neoplastic plasma cells. Values shown are the K-S D values for the separation of test (either CD126- or CD130-PE fluorescence) and control (CD3-PE fluorescence) cumulative frequencies. P values shown are for the difference in expression levels of the patient group and normal plasma cells in both cases (Mann-Whitney Utest).