IL-6 “rescue” from dexamethasone-induced apoptosis: dose-dependent inhibition in CD126⁺ cases with MRA

. The graph shows the number of viable plasma cells remaining after culture with dexamethasone, IL-6, and varying concentrations of MRA (humanized anti-CD126) for a CD126⁺ and a CD126⁻ patient. Plasma cell numbers are expressed as a proportion of the control (dexamethasone only).