Fig. 5.
Scatchard analysis of FcγRIIA on platelets and macrophages of FcγRIIA tg line 32 shows lower receptor density than tg line 11.
Measurement of 125I-labeled IV.3 antibody binding to FcγRIIA on platelets indicates approximately 450 receptors/cell, about 25% to 30% of the receptor density of the FcγRIIA tg line 11 mice. The receptor density on macrophages of FcγRIIA tg line 32 mice is approximately 18 000/cell, about 30% of the receptor density of FcγRIIA tg line 11.