Fig. 5.
Migration of cytokine-activated PMNLs toward LARC.
PMNLs were incubated with PHA-sup (A), TNF-α (1 ng/mL), and GM-CSF (0.05 ng/mL) (B), or TNF-α (1 ng/mL) and IFN-γ (25 U/mL) (C) for 6 hours. Activated PMNLs were tested for their ability to respond to various concentrations of LARC (1-1000 ng/mL). fMLP (10−8mol/L) and IL-8 (100 ng/mL) were used as positive controls.