Lysosomal enzyme levels.

Lysosomal enzyme levels are abnormal in some cno/cnotissues. (A) (B) (C) β-glucuronidase (panel A), α-galactosidase (panel B), and β-galactosidase (panel C) activity in kidneys, liver, spleen, and platelets from cno/cno mice. Results are expressed as the percentage of wild-type activity (100%), indicated by the dashed line in each panel. Enzyme levels are significantly increased in cno/cno kidney and liver, but not spleen or platelets. **P < .01; ***P < .001; n = 5 for all determinations.