Fig. 1.
NK-cell–mediated cytotoxicity of pfp and IFN-γ gene-targeted mice.
Resting splenocytes and IL-2–activated adherent spleen NK cells were assessed by 4-hour 51Cr release assays using labeled targets as indicated for (A) B6 or (B) BALB/c strains of mice. An effector–target ratio of 100:1 is shown (4 were examined). The spontaneous release of 51Cr was always less than 15% (subtracted from test), and each experiment was performed twice using triplicate samples.
