Pertussis toxin inhibits HUVECs chemotaxis induced by I-309, vMIP-I, and LCM.

I-309, vMIP-I, and LCM, prepared as detailed in the legend for Figure3, were tested for chemotactic activity using HUVECs pretreated with either pertussis or cholera toxin as described in “Materials and methods.” Pertussis toxin inhibited HUVEC chemotaxis in response to all 3 agonists (*P < .001), whereas cholera toxin did not inhibit. hpf, high power field.