Fig. 3.
KGF suppresses the in vivo allogeneic MLR.
C57BL/6 mice were given KGF (5 mg/kg per day) sc on days −3, −2, and −1, followed by injection of 5 × 107 irradiated BALB/c spleen cells intraperitoneally on day 0. Splenocytes were taken 7 days after in vivo alloimmunization, and secondary in vitro MLR was set up at the indicated responder:stimulator ratios. Data are presented as mean ± SE for 3 mice per group. P < .001 for KGF (●) versus PBS (○) by ANOVA. One of 3 reproducible experiments is shown.
