Fig. 5.
KGF facilitates engraftment of T cells, B cells and monocytes.
Recipient mice from Figure 4 are shown. KGF schedules are as follows: KGF-1, days −4, −3, and −2 before BMT; KGF-2, days −4, −3, −2, and 0 to 14 (every day); KGF-3, days −4, −3, −2, and 3 times a week from day 0 through 14. Engraftment of donor T cells (CD4, CD8), B cells (CD19), and monocytes (Mac-1) was evaluated on day 105 after BMT by FACS as described in “Materials and methods.” Mean values are indicated for 6 mice per group. PBS indicates non-KGF–treated C57BL/6 recipients of BALB/c BM, most of which reject the BM grafts.