Fig. 3.
Fig. 3. IFN-γ and agonistic anti-fas antibody treatment triggers an apoptotic response. / The HSC536N, HSC536N FANCC/neo, and HSC536N FANCC cells were exposed to either 1 ng/mL IFN-γ for 48 hours or to IFN-γ for 24 hours followed by 24 hours of exposure to 100 ng/mL fas antibody before cells were harvested and analyzed for apoptosis using the TUNEL assay. Pretreatment with 25 μmol/L Z-DEVD-FMK blunted the apoptotic response in all 3 cell lines.

IFN-γ and agonistic anti-fas antibody treatment triggers an apoptotic response.

The HSC536N, HSC536N FANCC/neo, and HSC536N FANCC cells were exposed to either 1 ng/mL IFN-γ for 48 hours or to IFN-γ for 24 hours followed by 24 hours of exposure to 100 ng/mL fas antibody before cells were harvested and analyzed for apoptosis using the TUNEL assay. Pretreatment with 25 μmol/L Z-DEVD-FMK blunted the apoptotic response in all 3 cell lines.

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