Effect of sodium orthovanadate on SDF-1α–induced chemotaxis of CXCR4 L1.2 cells, Jurkat cells, and PBLs.

CXCR4 L1.2 (A), Jurkat (B), or PBL (C) cells were untreated (0) or pretreated with different concentrations of sodium orthovanadate for 45 minutes. Migration toward 25 ng/mL SDF-1α was measured after 3 hours. Chemotaxis of cells in the absence of inhibitor is considered 100% migration. *P < .05; **P < .005.