Fig. 3.
Fig. 3. Competitive binding of native IL-4 and BAY 36-1677. / The relative affinity of native IL-4 (○) and BAY 36-1677 (●) for IL-4Rα was compared using a solid-phase binding assay as described in “Patients, materials, and methods.” Using this assay format, the absolute KI values were calculated to be 2.8 × 10−9 M (95% CI, 2.3 to 3.5 × 10−9 M) and 6.1 × 10−10 M (95% CI, 4.9 to 7.4 × 10−10 M), respectively.

Competitive binding of native IL-4 and BAY 36-1677.

The relative affinity of native IL-4 (○) and BAY 36-1677 (●) for IL-4Rα was compared using a solid-phase binding assay as described in “Patients, materials, and methods.” Using this assay format, the absolute KI values were calculated to be 2.8 × 10−9 M (95% CI, 2.3 to 3.5 × 10−9 M) and 6.1 × 10−10 M (95% CI, 4.9 to 7.4 × 10−10 M), respectively.

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