Effect of BAY 36-1677 (25 ng/mL) on stroma-supported cultures of normal CD34⁺ cells from cord blood.

At the beginning of the culture (left panel), most cells had high CD34 expression. After 7 days of culture, maturing myeloid cells with CD13 and CD33 expression and low or absent CD34 appeared (center and right panels). The number of cells recovered in cultures with and without the variant IL-4 was identical, but immature cells with high CD34 expression were predominant with BAY 36-1677.