Location of PCR primers in intron 5 of

TEL and intron 1 of AML1.Arrows indicate the location and direction of primers used in this study. In TEL gene all primers were located within the 4.2-kb HindIII fragment of intron 5. E1F, E2F, and E3F were used for LM-PCR analysis and E3F, E4F, E1R, and E2R were used for inverse PCR analysis. In AML1 gene, 2 sets of primers for LM-PCR analysis (A1R, A2R, A3R, and A4R) were located within 2 kb of one long purine-pyrimidine repeat (about 55 kb downstream of exon 1) in intron 1. Numbered solid boxes indicate the exons of each gene. Hatched boxes (Pu/Py) represent alternative purine-pyrimidine tract located on each gene. H: HindIII, E: EcoRI.