Nucleotide sequences of DSB ends of the

TEL and AML1 genes. (A) Nucleotide sequences of DNA break ends of the TEL andAML1 genes obtained from the RS4;11 or TS-2 cell line. BW1 represents the sequence of BW linker connected to each DNA break end. Underlined letters indicate nontemplated nucleotide inserts between BW linker and DNA break ends with no homology to germline sequence. Arrows indicate the breakpoint of genomic sequence observed in DSBs. One identical breakpoint in intron 5 of TEL gene and 4 different breakpoints in intron 1 of AML1 gene were isolated. (B) Nucleotide sequences of DSB ends of AML1 gene obtained from EB-LCL induced by chemical agents. (C) Nucleotide sequences of DSB ends of the TEL and AML1 gene obtained from cord blood samples after 24 hours of serum starvation.