Fig. 6.
Fig. 6. Inhibitory effects of autoantibodies on binding of FVIII fragments to anhydro-APC. / Serial dilutions of autoantibody F(ab′)2 were incubated with 0.2 μM intact FVIII (A), 80-kd LCh, or 72-kd LCh (B) for 2 hours at 37°C before being added to immobilized anhydro-APC. Case 1, ○; case 2, ●; case 3, ■; type 1 autoantibody F(ab′)2, ▪.

Inhibitory effects of autoantibodies on binding of FVIII fragments to anhydro-APC.

Serial dilutions of autoantibody F(ab′)2 were incubated with 0.2 μM intact FVIII (A), 80-kd LCh, or 72-kd LCh (B) for 2 hours at 37°C before being added to immobilized anhydro-APC. Case 1, ○; case 2, ●; case 3, ■; type 1 autoantibody F(ab′)2, ▪.

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