Pattern of TH1 (IFN-γ and IL-12p70) and TH2 (IL-4 and IL-10) cytokine production following T-cell–depleted allogeneic BMT.

At 2 and 5 weeks after transplantation, recipient C3H/HeJ mice, irradiated and reconstituted as in Figure 1 legend, were assessed for cytokine production by means of specific ELISAs. Cytokines were assessed in culture supernatants of splenocytes stimulated with mitogen for 48 hours. *Indicates P < .05 (BMT mice vs donor mice).